Micronutrients
Prescription EPA cut cardiac events; the same dose off a shelf has not been shown to.
Not yet investigated
Prescription EPA cut cardiac events; the same dose off a shelf has not been shown to.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Why 'fish oil' is not one question. Reading REDUCE-IT alongside ASCEND and VITAL, the authors conclude the benefit tracks FORMULATION and DOSE: high-dose PURE eicosapentaenoic acid reduced atherosclerotic events where mixed EPA/DHA preparations at ordinary doses did not. A trial of a 4 g pure-EPA prescription drug says nothing about a 1 g supermarket capsule, and both get reported as 'omega-3'.
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Also in Micronutrients
The letter
The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.
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