Botanicals & extracts
A herb famous for a psychosis it does not cause, with a small steroid-sparing trial in Crohn's that nobody has replicated.
Not yet investigated
A herb famous for a psychosis it does not cause, with a small steroid-sparing trial in Crohn's that nobody has replicated.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Forty patients across five German sites, tapered off steroids over ten weeks. 13 of 20 on wormwood reached near-complete symptom remission and held it to week 20; 16 of 20 on placebo needed steroids restarted. That is a striking result in a disease with few steroid-sparing options — and it is forty people, in one trial, from 2007, never replicated. Treat it as the reason to run a bigger trial, not as a reason to take it.
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The letter
The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.
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