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Antiparasitic drugs

Artemisinin

Pulled from a 1,600-year-old Chinese fever recipe, extracted cold because heat destroyed it, and now the backbone of malaria treatment.

Filed under Drug Constellation Antiparasitic drugs Status Upcoming

Not yet investigated

What we have so far

Pulled from a 1,600-year-old Chinese fever recipe, extracted cold because heat destroyed it, and now the backbone of malaria treatment.

This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.

What we are reading

Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.

  1. Tu Y. The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine.Nat Med · 2011 · 17(10):1217–122010.1038/nm.2471 · PMID 21989013

    Her own account, four years before the Nobel. The detail that matters for this show: the classical text said to steep the herb in cold water and wring it out, and that instruction is why the extraction worked — artemisinin degrades with heat, so the conventional hot extraction had been destroying it. The tradition did not contain the pharmacology. It contained the method, and somebody had to notice.

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