Immune
In lupus and RA, self-antibodies appear years before symptoms; boosting is the wrong verb.
Not yet investigated
In lupus and RA, self-antibodies appear years before symptoms; boosting is the wrong verb.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Review, used here as the worked example of an autoimmune disease rather than as a source on autoimmunity generally — replace with a broader epidemiological source before broadcast. Two things to carry forward: MS prevalence is rising for two different reasons that get conflated (earlier diagnosis and longer survival, AND a true rise in incidence), and the disease is framed as a gene-by-environment interaction rather than either alone.
Connected on the map
Also in Immune
The letter
The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.
No sponsors · No supplement affiliates · Unsubscribe any time
