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Immune

Helminth immunomodulation

Worm exposure tracks LOWER rates of autoimmune and metabolic disease. The immunology runs opposite to the folklore about parasites.

Filed under Hypothesis Constellation Immune Status Upcoming

Not yet investigated

What we have so far

Worm exposure tracks LOWER rates of autoimmune and metabolic disease. The immunology runs opposite to the folklore about parasites.

This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.

What we are reading

Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.

  1. Sipahi AM, Baptista DM. Helminths as an alternative therapy for intestinal diseases.World J Gastroenterol · 2017 · 23(33):6009–601510.3748/wjg.v23.i33.6009 · PMID 28970717

    EDITORIAL, not a trial or a systematic review — treat as orientation only. Its own honest line is the one to keep: there is some evidence on safety and tolerability, but 'evidence about their impact on disease activity is lacking'. Species, dose, timing and mechanism are all still open. This is the cautionary half of the hygiene-hypothesis story.

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The letter

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The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.

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