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Mood & neurochemistry

GSK-3beta

The enzyme joining lithium, insulin signalling and tau phosphorylation — and the least famous node on this map.

Filed under Enzyme Constellation Mood & neurochemistry Status Upcoming

Not yet investigated

What we have so far

The enzyme joining lithium, insulin signalling and tau phosphorylation — and the least famous node on this map.

This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.

What we are reading

Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.

  1. Duthie A, et al. Pilot Trial of Lithium in Humans With Mild Cognitive Impairment (GSK-3 target engagement).Front Mol Neurosci · 2019 · 12:16310.3389/fnmol.2019.00163 · PMID 31316348

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The letter

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The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.

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