Sleep & circadian
About twenty thousand neurons above the optic chiasm, set by light through the eye.
Not yet investigated
About twenty thousand neurons above the optic chiasm, set by light through the eye.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Review from the MRC LMB. The SCN is the principal circadian timekeeper of mammals, built on a transcription–translation feedback loop (Per/Cry against Clock/Bmal1) that exists in ALL major tissues — the SCN's job is co-ordinating them, not keeping the only clock. Also flags astrocytes in the SCN network, which is newer than most popular accounts.
Connected on the map
Also in Sleep & circadian
The letter
The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.
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