Not yet investigated
What we have so far
From cinchona bark. Banned by the FDA for leg cramps in 2010 after deaths from thrombocytopenia, and still sold in tonic water.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.