The most effective antifouling paint ever put on a hull, and a nanomolar agonist at the two nuclear receptors that decide whether a cell becomes a fat cell.
Filed under CompoundConstellation Tin & the obesogensStatus Upcoming
Not yet investigated
What we have so far
The most effective antifouling paint ever put on a hull, and a nanomolar agonist at the two nuclear receptors that decide whether a cell becomes a fat cell.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Grün F, Blumberg B. Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling.Endocrinology · 2006 · 147(6 Suppl):S50–510.1210/en.2005-1129 · PMID 16690801
Tributyltin and triphenyltin as nanomolar agonists at RXRα/β/γ and PPARγ. A review advancing the obesogen hypothesis — the receptor pharmacology is solid, the human obesity claim is the hypothesis, and the two should not be quoted as one thing.
