Bacteria
The precedent everybody forgot: a bacterium causing ulcers and gastric cancer, dismissed for a decade, then a Nobel Prize.
Not yet investigated
The precedent everybody forgot: a bacterium causing ulcers and gastric cancer, dismissed for a decade, then a Nobel Prize.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
240,000 adults in Taiwan. The PRIMARY outcome was null: inviting people to H. pylori screening did not reduce gastric cancer incidence or mortality versus colorectal screening alone. Only a POST HOC analysis adjusting for participation and follow-up found lower incidence (0.79, 0.63–0.98) — and still no mortality benefit. Anyone citing this as proof that eradication prevents gastric cancer is citing the post-hoc number, and the episode should say which number it is using.
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Also in Bacteria
The letter
The full citation list for each investigation, the studies that didn't make the episode, and any corrections — sent the morning it publishes.
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