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Protozoa

Trichomonas vaginalis

Wet-mount microscopy found 26% of what PCR found in one 980-woman comparison — the commonest curable STI, missed by the test most often used.

Filed under Pathogen Constellation Protozoa Status Upcoming

Not yet investigated

What we have so far

Wet-mount microscopy found 26% of what PCR found in one 980-woman comparison — the commonest curable STI, missed by the test most often used.

This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.

What we are reading

Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.

  1. Kim TG, Young MR, Goggins ER, et al. Trichomonas vaginalis in pregnancy: patterns and predictors of testing, infection, and treatment.Obstet Gynecol · 2020 · 135(5):1136–114410.1097/AOG.0000000000003776 · PMID 32282605

    3,265 pregnant women; 980 tested by BOTH wet mount and NAAT, so the comparison is within-patient. Microscopy sensitivity 26%, specificity 99% — it almost never calls a false positive and misses three quarters of the true ones. Prevalence 15%. Also worth saying on air: 29% of the retested women were positive again, which is a reinfection problem, not a drug-failure problem.

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