It completes its whole life cycle inside one host, so it persists for decades — and steroids turn that into hyperinfection with 60% ICU mortality.
Filed under PathogenConstellation RoundwormsStatus Upcoming
Not yet investigated
What we have so far
It completes its whole life cycle inside one host, so it persists for decades — and steroids turn that into hyperinfection with 60% ICU mortality.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.
What we are reading
Gathered for the investigation and not yet written up. Each note says what the paper does and does not show.
Geri G, Rabbat A, Mayaux J, et al. Strongyloides stercoralis hyperinfection syndrome: a case series and a review of the literature.Infection · 2015 · 43(6):691–69810.1007/s15010-015-0799-1 · PMID 26008854
133 ICU patients. 83.5% were on long-term corticosteroids; in-ICU mortality 60.3%. Two details for the episode: shock was usually driven by a concomitant gram-negative infection carried by the migrating larvae, and eosinophilia was present in only about a third — so the test people rely on is least reliable exactly when the stakes are highest.