Not yet investigated
What we have so far
Obesity is a state of high leptin, not low. Giving more does nothing except in the handful of people with a real deficiency — and in them it is transformative.
This star is on the map because the show intends to take the question apart properly — the trials, how it is actually tested, whether the thing sold is the thing studied. That work is not done yet, and nothing here should be read as a conclusion. When the investigation is published it will appear on this page.